The lab is devoted to the application of peptide and DNA science in multidisciplinary research activities at the interface of chemistry, biology and materials. Our expertise and research interests are wide in scopes, including:
- Design and synthesis of bioactive peptides/peptidomimetics for drug development
- Chemistry for protein engineering
- Peptide & DNA based analytical platforms
- Supramolecular chemistry and nanomaterials
Our research takes advantage of several national and international collaborative projects, with a strong focus in technology development.
We provide custom services related to peptide synthesis
Bioactive peptides, Peptidomimetics, Protein Chemistry
Peptide & DNA bioprobes for microanalytics
Peptide & DNA Materials
Alessandro Gori, PhD – Research Scientist
Greta Bergamaschi, PhD – Research Scientist
- Microwave-assisted peptide synthesis
- Native chemical ligation
- HPLC (Diode array, UV, RID)
- Spectroscopy (UV, CD, FT-IR)
Stabilization of the cysteine-rich conotoxin MrIA by using a 1,2,3-triazole as disulfide bond mimetic
Gori, A., Wang, C. A., Harvey, P.J., Rosengren, K.J., Bhola, R.F., Gelmi, L., Longhi, R., Christie, R. J., Lewis, R.J., Alewood, P.F. and Brust, A.
Angewandte Chemie 2015, 54, 1361 –1364 .
Screening complex biological samples with peptide microarrays: the favorable impact of probe orientation via chemoselective immobilization strategies on clickable polymeric coatings
Gori, A., Sola,L., Gagni,P., Bruni, G., Liprino,M., Peri, C., Colombo, G., Cretich, M. and Chiari, M.
Bioconj. Chem., 2016, 27(11), 2669-2677
A self-assembling peptide hydrogel for ultrafast 3D bioassays
Gagni, P., Romanato, A., Bergamaschi, G., Bettotti, P., Vanna, R., Piotto, C., Morasso, C., Chiari, M., Cretich, M. and Gori, A.
Nanoscale Adv., 2019, 1, 490–497
A halogen bond-donor amino acid for organocatalysis in water
Bergamaschi, G., Lascialfari, L., Pizzi, A., Martinez Espinoza, M.I., Demitri, N., Milani, A., Gori, A., and Metrangolo, P.
Chem. Comm. (2018) 54(76), 10718-10721
Contacts & Opportunities
Masters thesis and research training projects are available, students are welcome to apply. A 6-months notice is advisable.
PhD and Post Doc positions will be not advertised, if you are interested in joining our lab please send directly an application including your full CV and a motivation letter to: